PXD031217

PXD031217 is an original dataset announced via ProteomeXchange.

Title	Small molecule inhibitors of lysyl oxidases synergize with 5-azacytidine to restore erythropoiesis in myeloid neoplasms
Description	In this study, we assessed the effects of lysyl oxidase (LOX/LOXL) inhibition on the composition of extracellular matrix (ECM) produced by in vitro expanded bone marrow derived mesenchymal stromal cells (MSCs) of n=3 patients with myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN).
HostingRepository	PRIDE
AnnounceDate	2023-02-17
AnnouncementXML	Submission_2023-02-17_04:14:26.866.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	VictorCostina
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monomethylated residue; S-carboxamidoethyl-L-cysteine; dehydrated residue; phosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	TripleTOF 6600

Revision	Datetime	Status	ChangeLog Entry
0	2022-01-25 00:41:04	ID requested
⏵ 1	2023-02-17 04:14:27	announced

Dataset with its publication pending

submitter keyword: MSC, LC-MS, human,ECM

EvelynJaeger
contact affiliation	Institute for Clinical Chemistry, UMM Mannheim, Germany
contact email	jaeger.evelyn@umm.de
lab head
VictorCostina
contact affiliation	Institute for Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg
contact email	Victor.Costina@medma.uni-heidelberg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD031217

PRIDE project URI

• PRIDE
  1. PXD031217
     1. Label: PRIDE project
     2. Name: Small molecule inhibitors of lysyl oxidases synergize with 5-azacytidine to restore erythropoiesis in myeloid neoplasms