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PXD031197

PXD031197 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTurboID-based proximity labeling to identify LONP1-targeting proteins
DescriptionIt is documented that intracellular succinate levels are maintained and regulated by mitochondrial complexes II. In order to define the LONP1-dependent regulators of succinate content, unbiased TurboID-based proximity labeling was employed to exploit LONP1-targeting proteins. Our results showed that 63.5% of the proteins identified by LONP1-N-TurboID-based proximity labeling are mitochondrial proteins. Functional protein association networks analysis of the identified proteins indicated that these biotinylated proteins are related to carboxylic acid metabolic process, mitochondrial organization and mitochondrial gene expression.
HostingRepositoryPRIDE
AnnounceDate2023-04-08
AnnouncementXMLSubmission_2023-04-08_05:00:23.801.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLeiFang
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-01-24 03:15:41ID requested
12023-04-08 05:00:24announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: LONP1, Human,TurboID
Contact List
LeiFang
contact affiliationMedical School of Nanjing University, China
contact emailnjfanglei@nju.edu.cn
lab head
LeiFang
contact affiliationNanjing University Medical School
contact emailnjfanglei@nju.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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