PXD031197 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | TurboID-based proximity labeling to identify LONP1-targeting proteins |
Description | It is documented that intracellular succinate levels are maintained and regulated by mitochondrial complexes II. In order to define the LONP1-dependent regulators of succinate content, unbiased TurboID-based proximity labeling was employed to exploit LONP1-targeting proteins. Our results showed that 63.5% of the proteins identified by LONP1-N-TurboID-based proximity labeling are mitochondrial proteins. Functional protein association networks analysis of the identified proteins indicated that these biotinylated proteins are related to carboxylic acid metabolic process, mitochondrial organization and mitochondrial gene expression. |
HostingRepository | PRIDE |
AnnounceDate | 2023-04-08 |
AnnouncementXML | Submission_2023-04-08_05:00:23.801.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | LeiFang |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-01-24 03:15:41 | ID requested | |
⏵ 1 | 2023-04-08 05:00:24 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: LONP1, Human,TurboID |
Contact List
LeiFang |
contact affiliation | Medical School of Nanjing University, China |
contact email | njfanglei@nju.edu.cn |
lab head | |
LeiFang |
contact affiliation | Nanjing University Medical School |
contact email | njfanglei@nju.edu.cn |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/04/PXD031197 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD031197
- Label: PRIDE project
- Name: TurboID-based proximity labeling to identify LONP1-targeting proteins