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PXD031069

PXD031069 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDiscovery of Novel Circulating Immune Complexes in Lupus Nephritis Using Immunoproteomics
DescriptionThe goal is to discover novel circulating immune complexes (ICx) in the serum of Lupus Nephritis (LN) as potential biomarkers. Protein A/G magnetic beads or C1q-coated plates were used to capture ICx in the serum of LN, followed by the identification of immunoglobulin-binding proteins using liquid chromatography and tandem mass spectrometry (LC-MS/MS). Six related genomic-level databases were used for selecting potential biomarkers, following ELISA validation with independent samples.
HostingRepositoryPRIDE
AnnounceDate2022-05-20
AnnouncementXMLSubmission_2022-05-20_05:36:43.383.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterchenling tang
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-01-19 02:43:01ID requested
12022-05-20 05:36:44announced
Publication List
Tang C, Fang M, Tan G, Zhang S, Yang B, Li Y, Zhang T, Saxena R, Mohan C, Wu T, Discovery of Novel Circulating Immune Complexes in Lupus Nephritis Using Immunoproteomics. Front Immunol, 13():850015(2022) [pubmed]
Keyword List
submitter keyword: Human, MS/MS, Serum, Lupus Nephritis
Contact List
Tianfu Wu
contact affiliationTianfu Wu/Lab Dept. of Biomedical Engineering University of Houston
contact emailtwu13@central.uh.edu
lab head
chenling tang
contact affiliationuniversity of Houston
contact emailctang9@central.uh.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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