PXD030947

PXD030947 is an original dataset announced via ProteomeXchange.

Title	SWATH-MS identification of CXCL7, LBP, TGFβ1 and PDGFRβ as novel biomarkers in human systemic mastocytosis.
Description	We carried out a novel clinical biomarker investigation of the blood of systemic mastocytosis patients versus healthy controls; utilizing a new and emerging technology platform Sequential Window Acquisition of all Theoretical fragment-ion spectra mass spectrometry (SWATH-MS). This is the first use of this novel proteomic technique in the study of mastocytosis. A Swath-MS based biomarkers dsicovery study for systemic mastocytosis with orthogonal validation of biomarkers via ELISA.
HostingRepository	PRIDE
AnnounceDate	2022-05-20
AnnouncementXML	Submission_2022-05-20_06:49:03.482.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	bobby graham
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 6600

Revision	Datetime	Status	ChangeLog Entry
0	2022-01-14 00:32:30	ID requested
⏵ 1	2022-05-20 06:49:04	announced

Graham RLJ, McMullen AA, Moore G, Dempsey-Hibbert NC, Myers B, Graham C, as novel biomarkers in human systemic mastocytosis. Sci Rep, 12(1):5087(2022) [pubmed]

submitter keyword: Swath-MS, Biomarkers, Mastocytosis

Dr Ciaren Graham
contact affiliation	Deputy Head of School, School of Biological Sciences | 19 Chlorine Gardens| Belfast, BT9 5DJ Queen’s University Belfast | +44 28 9097 2383 | https://www.qub.ac.uk/schools/SchoolofBiologicalSciences/
contact email	ciaren.graham@qub.ac.uk
lab head
bobby graham
contact affiliation	Queens University Belfast
contact email	r.graham@qub.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD030947

PRIDE project URI

• PRIDE
  1. PXD030947
     1. Label: PRIDE project
     2. Name: SWATH-MS identification of CXCL7, LBP, TGFβ1 and PDGFRβ as novel biomarkers in human systemic mastocytosis.