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PXD030898

PXD030898 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification of interacting proteins with MDPs using IP-MS
Description	Mitochondria are important organelles controlling productivity and metabolism in cells. Recent studies have found that there are short open reading frames on mitochondrial genomes that has not been discovered before, which could encode short peptides, and we called them mitochondrial-derived peptides (MDPs), including MOTS-c encoded by 12S-rRNA, Humanin(HN) and SHLP1-6 encoded by 16S-rRNA. As a new class of circulating signaling molecules, these mitochondrial-derived peptides play an important function in certain human life activities or the occurrence of diseases. In order to study the potential unknown function of MDP and the molecular mechanism behind it, overexpressing MDPs were used as bait protein to conduct systematic immunoprecipitation experiment.
HostingRepository	iProX
AnnounceDate	2022-01-12
AnnouncementXML	Submission_2022-01-11_21:53:04.118.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhiwei Wang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-01-11 21:52:53	ID requested
⏵ 1	2022-01-11 21:53:04	announced

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: Humanin, MOTS-c, SHLP1-6, IP-MS

Contact List

Cuihong Wan
contact affiliation	Central China Normal University
contact email	ch_wan@ccnu.edu.cn
lab head
Zhiwei Wang
contact affiliation	Central China Normal University
contact email	969046765@qq.com
dataset submitter

Full Dataset Link List

iProX dataset URI