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PXD030884

PXD030884 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleS100A4/TCF complex transcription regulation drives epithelial-mesenchymal transition in chronic sinusitis through Wnt/GSK-3β/β-catenin signaling
DescriptionChronic rhinosinusitis (CRS) is closely associated with remodelling of nasal mucosal tissue during a prolonged inflammatory process, and epithelial mesenchymal transition (EMT) is thought to be involved in this process, but the underlying mechanisms driving this progression are unclear. Using a high-resolution Q Exactive Plus Orbitrap mass spectrometer, we performed a proteomic screen of CRS nasal mucosal tissue to identify differentially expressed proteins.
HostingRepositoryPRIDE
AnnounceDate2022-02-21
AnnouncementXMLSubmission_2022-02-21_10:58:07.756.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterNingyue Gong
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-01-11 01:21:23ID requested
12022-02-21 10:58:08announced
Publication List
Gong N, Shi L, Bing X, Li H, Hu H, Zhang P, Yang H, Guo N, Du H, Xia M, Liu C, -Catenin Signaling. Front Immunol, 13():835888(2022) [pubmed]
Keyword List
submitter keyword: CRS, Epigenetic regulation, EMT, S100A4, Inflammation
Contact List
S100A4/TCF complex transcription regulation drives epithelial-mesenchymal transition in chronic sinusitis through Wnt/GSK-3β/β-catenin signaling
contact affiliationPrecision Medicine Research Center, School of Pharmacy, Binzhou Medical University, Yantai, Shandong Province, 264003, PR China
contact emailjia.mi@bzmc.edu.cn
lab head
Ningyue Gong
contact affiliationShandong University
contact emailgongningyue158@gmail.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
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