PXD030838

PXD030838 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Deep proteome analysis of mouse brains from wild-type, LPS-induced, and drug-treated mice groups
Description	We studied the effect of bacterial Lipopolysaccharides on inducing neuroinflammation in mice. In addition, we investigated the effect of novel LAT1-utilizing anti-inflammatory derivatives on reversing this LPS-induced neuroinflammation status. Thus, we performed deep proteome analysis of mouse brains after treatment with vehicle, LPS, and LPS with LAT1-utilizing derivatives. The objective is to follow the different inflammatory biomarkers in the mouse brain and explain the inflammatory process after the LPS treatment with and without the LAT1-utilizing prodrugs.
HostingRepository	PRIDE
AnnounceDate	2022-10-25
AnnouncementXML	Submission_2022-10-25_12:03:53.880.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	AhmedMontaser
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	Bruker Daltonics timsTOF series

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-01-08 03:32:02	ID requested
⏵ 1	2022-10-25 12:03:54	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: neuroinflammation,Mouse, LAT1, diaPASEF, proteome

submitter keyword: neuroinflammation,Mouse, LAT1, diaPASEF, proteome

Contact List

ZbyněkZdráhal
contact affiliation	Head of Core Facility, Central European Institute of Technology, Masaryk University, Brno, Czech Republic.
contact email	zdrahal@sci.muni.cz
lab head
AhmedMontaser
contact affiliation	University of Eastern Finland
contact email	ahmed.montaser@uef.fi
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD030838
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD030838

PRIDE project URI

Repository Record List

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