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PXD030748

PXD030748 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMouse retina from Msi1/Msi2 double knockout in photoreceptor cells
DescriptionThis quantitative protepomics study (TMT10 isobaric labeling) of the protein expression in the retina of Msi1/Msi2 double knockout mouse compared to floxed controls. The Msi1 and Msi2 genes were knocked out in photoreceptor cells using tamoxifen inducible Cre (Cre-ERT2) under the control of Pde6g promoter. Tamoxifen was administered by intrapertoneal injection for three consecutive day starting at postnatald day 30, and the retina was collected at postnatal day 51. Retinas from floxed animals lacking the Cre recombinase and treated with tamoxifen were used as controls. Five biological replicates for each knockout (three femailes, two males) and control (two femaes and three males) group were used.
HostingRepositoryPRIDE
AnnounceDate2022-03-10
AnnouncementXMLSubmission_2022-03-10_09:37:17.110.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD030748
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterPeter Stoilov
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Eclipse
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-01-05 12:56:53ID requested
12022-03-10 09:37:17announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Mouse, retina, Msi1, Msi2, photorecptor, knockout
Contact List
Peter Stoilov
contact affiliationWest Virginia University
contact emailpstoilov@hsc.wvu.edu
lab head
Peter Stoilov
contact affiliationWest Virginia University
contact emailpstoilov@hsc.wvu.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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