PXD030746

PXD030746 is an original dataset announced via ProteomeXchange.

Title	Data in support of Gold micro-particles for knee osteoarthritisGold micro-particles for knee osteoarthritis
Description	This study investigated the effect of intraarticular gold micro particle implants for the treatment of pain and inflammation in KOA. The present open, exploratory, proof-of-concept study investigated whether intraarticular gold ions could act as a KOA treatment option through modulation of inflammatory mediators, pain sensitivity, and central pain mechanisms. The primary aim of this study were 1) to measure the effect on pain and function after intra-articular injection of 20 mg gold microparticles > 20 µm into the KOA joint using the patient’s synovial fluid (SF) as a carrier and 2) measure associated possible proteomic changes in the SF and serum.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:41:21.420.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Allan Stensballe
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2022-01-05 12:52:05	ID requested
1	2022-12-03 05:19:09	announced
2	2023-11-14 08:11:37	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 05:41:22	announced	2024-10-22: Updated project metadata.

Rasmussen S, Kjaer Petersen K, Kristiansen MK, Skallerup J, Aboo C, Thomsen ME, Skjoldemose E, J, ø, rgensen NK, Stensballe A, Arendt-Nielsen L, Gold micro-particles for knee osteoarthritis. Eur J Pain, 26(4):811-824(2022) [pubmed]

10.1002/ejp.1909;

submitter keyword: osteoartritits, pain, proteomics, gold, inflammation

Allan Stensballe
contact affiliation	Aalborg University
contact email	as@hst.aau.dk
lab head
Allan Stensballe
contact affiliation	Aalborg University
contact email	as@hst.aau.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/12/PXD030746

PRIDE project URI

• PRIDE
  1. PXD030746
     1. Label: PRIDE project
     2. Name: Data in support of Gold micro-particles for knee osteoarthritisGold micro-particles for knee osteoarthritis