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PXD030744

PXD030744 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLabel-free Quantitative Proteomics Approach to Unravel the Jerusalem artichoke (Helianthus tuberosus L.) Tuber
DescriptionThe present research investigates a ‘medicinal’ plant Jerusalem artichoke (abbreviated as JA) (Helianthus tuberosus L.) tuber proteome with an aim to unravel its proteome using a high-throughput proteomics technique. Although JA has been historically know to the Native Americans, it was brought back and spread to Europe by the colonists and in the late 19th century early 20th century it began to regain importance including its use for health and as a folk remedy for diabetes. In Japan (referred to as ‘kiku-imo’) its cultivation became popular mostly for health-related benefits such as reducing the blood sugar level. The group of (Genboku Takahashi et al.) has been working on the cultivation and utilization of kiku-imo tuber as a traditional/alternative medicine in daily life, and thus the research progressed to deeply look into the protein components through proteomics as very less is known about the proteome of the tubers, especially in relation to its importance as a functional food in treating diseases health conditions like diabetes. Using three commercially processed JA tuber products we used total protein extraction on the powdered samples in conjunction with label-free quantitate proteomic approach (mass spectrometry) to identify for the first time a comprehensive protein list for the JA tuber. A total of 2967 high‐confidence proteins were identified and categorized into different protein classes through bioinformatics. We have discussed these proteins especially in relation to their association with health and disease regulatory metabolism.
HostingRepositoryPRIDE
AnnounceDate2022-02-21
AnnouncementXMLSubmission_2022-02-21_10:53:50.474.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSun Tae Kim
SpeciesList scientific name: Helianthus tuberosus; NCBI TaxID: 4233;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-01-05 12:45:18ID requested
12022-02-21 10:53:51announced
Publication List
Bakku RK, Gupta R, Min CW, Kim ST, Takahashi G, Shibato J, Shioda S, Takenoya F, Agrawal GK, Rakwal R, L. (Jerusalem Artichoke, Kiku-Imo) Tuber Proteome by Label-Free Quantitative Proteomics. Molecules, 27(3):(2022) [pubmed]
Keyword List
submitter keyword: Jerusalem artichoke, Type 2 diabetes mellitus, Solid-phase extraction, LC-MS/MS
Contact List
Sun Tae Kim
contact affiliationDepartment of Plant Bioscience, Life and Industry Convergence Research Institute, Pusan National University, Miryang, 50463, Republic of Korea
contact emailstkim5505@gmail.com
lab head
Sun Tae Kim
contact affiliationPusan National University
contact emailstkim5505@gmail.com
dataset submitter
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Dataset FTP location
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