PXD030652

PXD030652 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Brain microvascular endothelial cells: PODXL KD
Description	The purpose of the present study was, therefore, to explore the effect of PODXL-knockdown on the protein expression and transport function in the immortalized human BMECs (hCMEC/D3) as a human BBB model. We established PODXL-knockdown hCMEC/D3 cells, and protein expressions were comprehensively analyzed using quantitative proteomics.
HostingRepository	jPOST
AnnounceDate	2022-03-11
AnnouncementXML	Submission_2022-09-18_02:34:18.472.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD030652
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Sumio Ohtsuki
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; O-phospho-L-serine; O-phospho-L-threonine
Instrument	instrument

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-12-27 17:08:25	ID requested
1	2022-03-10 07:00:07	announced
⏵ 2	2022-09-18 02:34:19	announced	2022-09-18: Updated FTP location.

Publication List

Nagano H, Ogata S, Ito S, Masuda T, Ohtsuki S, Knockdown of Podocalyxin Post-Transcriptionally Induces the Expression and Activity of ABCB1/MDR1 in Human Brain Microvascular Endothelial Cells. J Pharm Sci, 111(6):1812-1819(2022) [pubmed]

Nagano H, Ogata S, Ito S, Masuda T, Ohtsuki S, Knockdown of Podocalyxin Post-Transcriptionally Induces the Expression and Activity of ABCB1/MDR1 in Human Brain Microvascular Endothelial Cells. J Pharm Sci, 111(6):1812-1819(2022) [pubmed]

Keyword List

submitter keyword: Blood-brain barrier, podocalyxin, SWATH

submitter keyword: Blood-brain barrier, podocalyxin, SWATH

Contact List

Sumimo Ohtsuki
lab head
Sumio Ohtsuki
contact affiliation	Kumamoto University
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001434/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001434/