PXD030579

PXD030579 is an original dataset announced via ProteomeXchange.

Title	Glycosylated proteins identified for the first time in the alga Euglena gracilis
Description	Protein glycosylation, and in particular N-linked glycans, is a hall mark of Eukaryotic cells and has been well studied in mammalian cells and parasites. However, little research has been conducted to investigate the conservation and variation of protein glycosylation pathways in other eukaryotic organisms. Euglena gracilis is an industrially important microalga, used in the production of biofuels and nutritional supplements. It is evolutionarily highly divergent from green algae and more related to Kinetoplastid pathogens. It was recently shown that E. gracilis possesses the machinery for producing a range of protein glycosylations and make simple N-glycans, but the modified proteins were not identified. This study identifies the glycosylated proteins, including transporters, extra cellular proteases and those involved in cell surface signalling. Notably, many of the most highly expressed and glycosylated proteins are not related to any known sequences and are therefore likely to be involved in important novel functions in Euglena.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:46:14.705.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ellis O'Neill
SpeciesList	scientific name: Euglena gracilis; NCBI TaxID: 3039;
ModificationList	deamidated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2021-12-21 12:26:29	ID requested
1	2023-05-10 13:16:17	announced
⏵ 2	2023-11-14 08:46:19	announced	2023-11-14: Updated project metadata.

O'Neill EC, Glycosylated proteins in the protozoan alga Euglena gracilis: a proteomic approach. FEMS Microbiol Lett, 370():(2023) [pubmed]

submitter keyword: glycoproteins,Euglena gracilis

Ellis C O'Neill
contact affiliation	University of Nottingham
contact email	ellis.oneill@nottingham.ac.uk
lab head
Ellis O'Neill
contact affiliation	University of Nottingham
contact email	ellis.oneill@nottingham.ac.uk
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD030579
     1. Label: PRIDE project
     2. Name: Glycosylated proteins identified for the first time in the alga Euglena gracilis