PXD030455

PXD030455 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	DIA proteomic analysis of unstimulated murine bone marrow derived macrophages from WT, Nrf2 KO and Keap1 KD cells
Description	Unstimulated murine bone marrow derived macrophages cultured in L92 media from WT (4 biological replicates), Nrf2 KO (3 biological replicates) and Keap1 KD BMDM (3 biological replicates) were processed and analysed utilising DIA (label free) proteomic analysis. The Nrf2 KO mouse (DOI: 10.1006/bbrc.1997.6943 ) and Keap1 KD mouse ( DOI: 10.1128/MCB.01591-09) were previously published as noted.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:36:02.330.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alejandro Brenes
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; monohydroxylated residue; deaminated residue
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-12-16 12:05:02	ID requested
1	2022-04-28 01:07:39	announced
⏵ 2	2024-10-22 05:36:03	announced	2024-10-22: Updated project metadata.

Publication List

Ryan DG, Knatko EV, Casey AM, Hukelmann JL, Dayalan Naidu S, Brenes AJ, Ekkunagul T, Baker C, Higgins M, Tronci L, Nikitopolou E, Honda T, Hartley RC, O'Neill LAJ, Frezza C, Lamond AI, Abramov AY, Arthur JSC, Cantrell DA, Murphy MP, Dinkova-Kostova AT, Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response. iScience, 25(2):103827(2022) [pubmed]
10.1016/j.isci.2022.103827;

Ryan DG, Knatko EV, Casey AM, Hukelmann JL, Dayalan Naidu S, Brenes AJ, Ekkunagul T, Baker C, Higgins M, Tronci L, Nikitopolou E, Honda T, Hartley RC, O'Neill LAJ, Frezza C, Lamond AI, Abramov AY, Arthur JSC, Cantrell DA, Murphy MP, Dinkova-Kostova AT, Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response. iScience, 25(2):103827(2022) [pubmed]

10.1016/j.isci.2022.103827;

Keyword List

submitter keyword: DIA, KEAP1, NRF2, macrophages,BMDM, murine

submitter keyword: DIA, KEAP1, NRF2, macrophages,BMDM, murine

Contact List

Simon C. Arthur
contact affiliation	Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee
contact email	j.s.c.arthur@dundee.ac.uk
lab head
Alejandro Brenes
contact affiliation	Centre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh
contact email	ajbrenesmurillo@dundee.ac.uk
dataset submitter

Full Dataset Link List

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PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD030455

PRIDE project URI

Repository Record List

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