PXD030410

PXD030410 is an original dataset announced via ProteomeXchange.

Title	HRD1-ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination
Description	As a ubiquitin ligase, HRD1 may regulate FGF21 expression through targeting protein degradation. We then aimed to identify proteins whose expressions are altered at post-transcriptional levels in HRD1 LKO mouse liver
HostingRepository	iProX
AnnounceDate	2021-12-14
AnnouncementXML	Submission_2021-12-14_19:41:04.671.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chaozhi Jin
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	phosphorylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-12-14 19:40:29	ID requested
⏵ 1	2021-12-14 19:41:05	announced

Wei J, Chen L, Li F, Yuan Y, Wang Y, Xia W, Zhang Y, Xu Y, Yang Z, Gao B, Jin C, Melo-Cardenas J, Green RM, Pan H, Wang J, He F, Zhang K, Fang D, HRD1-ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination. EMBO J, 37(22):(2018) [pubmed]

submitter keyword: CREBH, ER-associated degradation, FGF21, HRD1, multi-organ crosstalk

Jian Wang
contact affiliation	State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China
contact email	wangjian@bmi.ac.cn
lab head
Chaozhi Jin
contact affiliation	State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China
contact email	jinx-1@163.com
dataset submitter

iProX dataset URI