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PXD030365

PXD030365 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLow-Density Lipoprotein Receptor fuels the cellular cholesterol-mTORC1 axis required for CD8+ T cell activation
DescriptionIn this study, the contribution of cholesterol uptake by the low-density-lipoprotein receptor (LDLR) in the metabolic reprogramming of activated T cells was investigated at proteome level by mass-spectrometry-assisted shotgun proteomics.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:54:47.808.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterGiangiacomo Beretta
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-12-13 07:12:25ID requested
12022-09-20 08:02:19announced
22023-11-14 08:54:48announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: mTORC1, cholesterol, LFQ,CD8+,LDLR
Contact List
Giangiacomo Beretta
contact affiliationDepartment of environmental science and policy, University of Milan, Milan, Italy
contact emailgiangiacomo.beretta@unimi.it
lab head
Giangiacomo Beretta
contact affiliationDepartment of environmental science and policy
contact emailgiangiacomo.beretta@unimi.it
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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