PXD030321 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | LC-MS/MS identification of interactors of Interleukin-1 Receptor Associated Kinase 3 (IRAK3) |
| Description | Imterleukin-1 Receptor Associated Kinase 3 (IRAK3) acts as a negative regulator of interleukin-1 receptor and Toll-like receptors signalling by preventing dissociation of IRAKs from myddosome complex, therefore disabling production of proinflammatory cytokines. Since the molecular mode of IRAK3 action remains unclear, a large scale protein-protein interaction study has been undertaken to identify interactors of IRAK3 in human monocytes. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-23 |
| AnnouncementXML | Submission_2026-08-22_23:13:39.562.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD030321 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Ilona Turek |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | carbamoylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | LTQ Orbitrap Elite |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2021-12-11 15:45:25 | ID requested | |
| ⏵ 1 | 2026-08-22 23:13:40 | announced | |
Publication List
Keyword List
| submitter keyword: THP-1, IRAK3, Co-IP, LC-MS/MS |
Contact List
| Helen Ruth Irving |
|---|
| contact affiliation | Department of Pharmacy and Biomedical Sciences, La Trobe University |
| contact email | h.irving@latrobe.edu.au |
| lab head | |
| Ilona Turek |
|---|
| contact affiliation | La Trobe University |
Australian Centre for Disease Development - CSIRO |
| contact email | i.turek@latrobe.edu.au |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD030321 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD030321
- Label: PRIDE project
- Name: LC-MS/MS identification of interactors of Interleukin-1 Receptor Associated Kinase 3 (IRAK3)
