PXD030318

PXD030318 is an original dataset announced via ProteomeXchange.

Title	Rabbit liver tissue infected with rabbit hemorrhagic disease virus (RHDV) LC-MS
Description	The rabbit hemorrhagic disease virus (RHDV) represents the causative agent of a highly contagious disease in rabbits that is often associated with high mortality. Because of the lack of a suitable cell culture system for RHDV, the pathogenic mechanism and replication of RHDV remains unclear. In order to analyze the pathogenic mechanism of RHDV to rabbits, we used New Zealand white rabbits infected with RHDV, collected liver tissues 32 hours after infection, and used TMT labeling for LC-MS analysis. Subsequently, it was compared and analyzed with the protein data of the liver tissue of the uninfected rabbits. Perform bioinformatics analysis on significantly different proteins. Finally, comprehensively analyze the influence of RHDV on host protein and pathway expression levels. This study provides clues to clarify the pathogenic mechanism of RHDV in rabbits.
HostingRepository	PRIDE
AnnounceDate	2022-05-19
AnnouncementXML	Submission_2022-05-19_08:59:25.842.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jie Zhu
SpeciesList	scientific name: Oryctolagus cuniculus; NCBI TaxID: 9986;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2021-12-11 15:41:18	ID requested
⏵ 1	2022-05-19 08:59:26	announced

Yang H, Zhu J, Guo H, Tang A, Chen S, Zhang D, Yuan L, Liu G, Molecular cloning, characterization, and functional analysis of the uncharacterized C11orf96 gene. BMC Vet Res, 18(1):170(2022) [pubmed]

submitter keyword: Rabbit, Liver, RHDV, LC-MS

Guangqing Liu
contact affiliation	Shanghai Veterinary Research Institute,Chinese Academy of Agricultural Sciences
contact email	liugq@shvri.ac.cn
lab head
Jie Zhu
contact affiliation	Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences
contact email	zj121@shvri.ac.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD030318

PRIDE project URI

• PRIDE
  1. PXD030318
     1. Label: PRIDE project
     2. Name: Rabbit liver tissue infected with rabbit hemorrhagic disease virus (RHDV) LC-MS