PXD030315

PXD030315 is an original dataset announced via ProteomeXchange.

Title	Proteomic profile of human CHME3 microglia in response to the miR-124-3p modulation in Swedish neuronal cells
Description	We aim to evaluate how the levels of miR-124 in APPSwedish neuronal change the signature of interferon-gamma-stimulated human microglia, in a co-culture system. We want to fing possible pathways involved in cell-to-cell signaling and traficking, as well as inflammation-associated and miRNA targets in microglia, with potential interest to be further explored in Alzheimer's disease field.
HostingRepository	PRIDE
AnnounceDate	2022-06-02
AnnouncementXML	Submission_2022-06-02_05:56:49.619.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Frank Stein
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-12-11 15:36:06	ID requested
⏵ 1	2022-06-02 05:56:49	announced

Dataset with its publication pending

submitter keyword: Neuron-microglia crosstalk

miRNA intercellular signaling

neuroimmune function

vesicular traficking

Dora Brites
contact affiliation	Neuroinflammation, Signaling and Neuroregeneration Laboratory, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisboa, Portugal
contact email	dbrites@ff.ulisboa.pt
lab head
Frank Stein
contact affiliation	EMBL
contact email	frank.stein@embl.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/06/PXD030315

PRIDE project URI

• PRIDE
  1. PXD030315
     1. Label: PRIDE project
     2. Name: Proteomic profile of human CHME3 microglia in response to the miR-124-3p modulation in Swedish neuronal cells