PXD030182

PXD030182 is an original dataset announced via ProteomeXchange.

Title	Multi-omics analysis into the molecular mechanisms underlying the up-regulation of HBG1/2 expression induced by HBB deletion
Description	A multi-omics study examining chromatin accessibility, transcriptome, proteome and phosphorylation patterns in the HBB homozygous knockout of the HUDEP2 cell line (HBB-KO)
HostingRepository	PRIDE
AnnounceDate	2022-05-31
AnnouncementXML	Submission_2022-05-31_06:35:38.721.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Guoqiang Zhou
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2021-12-05 04:40:26	ID requested
⏵ 1	2022-05-31 06:35:42	announced

Zhou G, Zhang H, Lin A, Wu Z, Li T, Zhang X, Chen H, Lu D, Gene-Knockout Human Erythroid Progenitor Cell Model. Int J Mol Sci, 23(5):(2022) [pubmed]

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project, Stems Cells (B/D-HPP)

submitter keyword: Omics-study

HBB

HBG1/2

HIF1 pathway

Stress erythropoiesis

Daru Lu
contact affiliation	State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, 200438, China
contact email	darulu@163.com
lab head
Guoqiang Zhou
contact affiliation	Fudan University
contact email	18110700067@fudan.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD030182

PRIDE project URI

• PRIDE
  1. PXD030182
     1. Label: PRIDE project
     2. Name: Multi-omics analysis into the molecular mechanisms underlying the up-regulation of HBG1/2 expression induced by HBB deletion