PXD030182 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Multi-omics analysis into the molecular mechanisms underlying the up-regulation of HBG1/2 expression induced by HBB deletion |
Description | A multi-omics study examining chromatin accessibility, transcriptome, proteome and phosphorylation patterns in the HBB homozygous knockout of the HUDEP2 cell line (HBB-KO) |
HostingRepository | PRIDE |
AnnounceDate | 2022-05-31 |
AnnouncementXML | Submission_2022-05-31_06:35:38.721.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Guoqiang Zhou |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-12-05 04:40:26 | ID requested | |
⏵ 1 | 2022-05-31 06:35:42 | announced | |
Publication List
Zhou G, Zhang H, Lin A, Wu Z, Li T, Zhang X, Chen H, Lu D, Gene-Knockout Human Erythroid Progenitor Cell Model. Int J Mol Sci, 23(5):(2022) [pubmed] |
Keyword List
ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project, Stems Cells (B/D-HPP) |
submitter keyword: Omics-study |
HBB |
HBG1/2 |
HIF1 pathway |
Stress erythropoiesis |
Contact List
Daru Lu |
contact affiliation | State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, 200438, China |
contact email | darulu@163.com |
lab head | |
Guoqiang Zhou |
contact affiliation | Fudan University |
contact email | 18110700067@fudan.edu.cn |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD030182 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD030182
- Label: PRIDE project
- Name: Multi-omics analysis into the molecular mechanisms underlying the up-regulation of HBG1/2 expression induced by HBB deletion