PXD030144
PXD030144 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Requirement of Rbx1 Cullin-RING ligase E3 and Ube2m neddylation E2 in the maintenance of the fitness of Treg cells |
Description | the Ube2m-Rbx1 axis is required for the maintenance of homeostasis and functions of Treg cells; and Rbx1 has Ube2m-independent roles in the fitness of Treg cells, suggesting a layer of complexity in neddylation activation of CRLs. |
HostingRepository | iProX |
AnnounceDate | 2021-12-03 |
AnnouncementXML | Submission_2022-10-12_19:42:47.420.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Mingwei Liu |
SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-12-02 20:03:35 | ID requested | |
1 | 2021-12-02 20:07:26 | announced | |
⏵ 2 | 2022-10-12 19:42:48 | announced | 2022-10-13: Update publication information. |
Publication List
Wu D, Li H, Liu M, Qin J, Sun Y, The Ube2m-Rbx1 neddylation-Cullin-RING-Ligase proteins are essential for the maintenance of Regulatory T cell fitness. Nat Commun, 13(1):3021(2022) [pubmed] |
Keyword List
submitter keyword: Rbx1, Treg cells, mice |
Contact List
Yi Sun | |
---|---|
contact affiliation | Institute of Translational Medicine, Zhejiang University School of Medicine |
contact email | yisun@zju.edu.cn |
lab head | |
Mingwei Liu | |
contact affiliation | Beijing Proteome Research Center |
contact email | mwliu@126.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |