PXD030017

PXD030017 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic analysis of Caenorhabditis elegans challenged with pseudomonas aeruginosa and the inhibitory effects of 6-methycoumarine
Description	Goal of the analysis was to identify proteomic changes in Caenorhabditis elegans upon infection with Pseudomonas aeruginosa PA01 and to compare to inhibitory effects of virulence factor inhibitor methycoumarine. Worms grown on media containing E. coli OP50 served as control. This was achieved through tandem mass-tags based quantitative proteomics approach coupled to LC-MS/MS methods. An Orbitrap Fusion Tribrid mass spectrometer (Thermo Fischer Scientific, Bremen, Germany) connected to the Easy- nLC-1200 nanoflow liquid chromatography system (Thermo Scientific) was used for data acquisition.
HostingRepository	PRIDE
AnnounceDate	2024-07-15
AnnouncementXML	Submission_2024-07-14_23:00:51.400.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Keshava Prasad T. S.
SpeciesList	scientific name: Caenorhabditis elegans; NCBI TaxID: 6239;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-11-28 06:09:20	ID requested
⏵ 1	2024-07-14 23:00:52	announced

Publication List

Ramesh P, Bajire SK, Kanichery A, Najar MA, Shastry RP, Prasad TSK, 6-Methylcoumarin rescues bacterial quorum sensing induced ribosome-inactivating stress in Caenorhabditis elegans. Microb Pathog, 173(Pt A):105833(2022) [pubmed]
10.1016/j.micpath.2022.105833;

Ramesh P, Bajire SK, Kanichery A, Najar MA, Shastry RP, Prasad TSK, 6-Methylcoumarin rescues bacterial quorum sensing induced ribosome-inactivating stress in Caenorhabditis elegans. Microb Pathog, 173(Pt A):105833(2022) [pubmed]

10.1016/j.micpath.2022.105833;

Keyword List

submitter keyword: Quantitative proteomics, TMT, 7-methyl coumarine, Pseudomonas aeruginosa PAO1, Caenorhabditis elegans

submitter keyword: Quantitative proteomics, TMT, 7-methyl coumarine, Pseudomonas aeruginosa PAO1, Caenorhabditis elegans

Contact List

T. S.S Keshava Prasad
contact affiliation	Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India
contact email	keshav@yenepoya.edu.in
lab head
Keshava Prasad T. S.
contact affiliation	Institute of Bioinformatics, Bangalore, Karnataka, India.
contact email	keshav@ibioinformatics.org
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD030017
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD030017

PRIDE project URI

Repository Record List

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