PXD029989

PXD029989 is an original dataset announced via ProteomeXchange.

Title	DIA Based quantitative proteomics analysis reveals MAPK pathway a important role onthe Tremella fuciformis dimorphism
Description	Tremella fuciformis is a dimorphic fungus that can undertake the reversible transition between yeast-like spores and hypha forms. In this project, we attempted to explore the differential proteins profile of dikaryotic yeast-like spores (FBMDS) and dikaryotic mycelium (DM) by applying the HRMS1-DIA full proteomics and PRM target proteomics synthetically. The results showed that a total of 5687 proteins were quantified, and 2220 of them (39.01%) showed more than a two-fold change in expression. The functional analysis of differential expression proteins (DEPs) confirmed that the DEPs were mainly located on membrane and nucleus, and FBMDS tended to express proteins involved in DNA replication and transcription, DNA damage repair, biosynthesis, and metabolism. At the same time, DM exhibited increased expression of signal transduction such as MAPK signaling pathway, Ras signaling pathway.
HostingRepository	PRIDE
AnnounceDate	2022-05-25
AnnouncementXML	Submission_2022-05-25_09:30:29.739.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Li Yaxing
SpeciesList	scientific name: Tremella; NCBI TaxID: 105767;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-11-26 10:34:07	ID requested
⏵ 1	2022-05-25 09:30:30	announced

Li Y, Tang H, Zhao W, Yang Y, Fan X, Zhan G, Li J, Sun S, Based on Comparative Proteomics. J Fungi (Basel), 8(3):(2022) [pubmed]

submitter keyword: Tremella fuciformis;dimorphism;MAPK signaling pathway

Sun Shujing
contact affiliation	College of Life Sciences, Fujian Agriculture and Forestry University,
contact email	shjsun2004@126.com
lab head
Li Yaxing
contact affiliation	Fujian argricuture and forestry university
contact email	fafu_lyx@163.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD029989
     1. Label: PRIDE project
     2. Name: DIA Based quantitative proteomics analysis reveals MAPK pathway a important role onthe Tremella fuciformis dimorphism