PXD029963

PXD029963 is an original dataset announced via ProteomeXchange.

Title	Computational Prediction, Validation and Repurposing of Existing Drug as Inhibitor of Vascular Calcification
Description	This study aimed to identify small molecules that inhibit vascular calcification with computational approach. To examine the mechanism of calcification inhibition, proteomics analysis was performed using aorta tissue samples to clarify therapeutic target.
HostingRepository	PRIDE
AnnounceDate	2022-02-17
AnnouncementXML	Submission_2022-02-17_05:51:01.786.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD029963
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Sasha Singh
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-11-26 04:17:51	ID requested
⏵ 1	2022-02-17 05:51:02	announced

Tanaka T, Asano T, Okui T, Kuraoka S, Singh SA, Aikawa M, Aikawa E, Computational Screening Strategy for Drug Repurposing Identified Niclosamide as Inhibitor of Vascular Calcification. Front Cardiovasc Med, 8():826529(2021) [pubmed]

submitter keyword: Drug discovery, drug repurposing, vascular calcification, mice, Wnt signaling, proteomics

Elena Aikawa
contact affiliation	Brigham Women's Hospital, Harvard medical school
contact email	eaikawa@bwh.harvard.edu
lab head
Sasha Singh
contact affiliation	Brigham and Women's Hospital, Harvard Medical School
contact email	sasingh@bwh.harvard.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD029963

PRIDE project URI

• PRIDE
  1. PXD029963
     1. Label: PRIDE project
     2. Name: Computational Prediction, Validation and Repurposing of Existing Drug as Inhibitor of Vascular Calcification