PXD029926

PXD029926 is an original dataset announced via ProteomeXchange.

Title	Lysosomal damage proteomics in HeLa cells
Description	To identify ubiquitylation targets following lysosomal damage in HeLa cells treated with LLOMe we performed quantitative ubiquitin-remmnant (diGly) profilig coupled to mass spectrometry (MS). In addition, we performed APEX2-based proximity biotinylation followed by MS analysis to identify proximity partners of one of the ubiquitylation targets (CNN2).
HostingRepository	PRIDE
AnnounceDate	2022-06-23
AnnouncementXML	Submission_2022-06-23_05:13:39.443.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Christian Behrends
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	carbamoylated residue; ubiquitinylated lysine; monohydroxylated residue
Instrument	Q Exactive HF; LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2021-11-26 02:02:28	ID requested
⏵ 1	2022-06-23 05:13:39	announced

Dataset with its publication pending

submitter keyword: Lysosome, LLOMe, ubiquitin, diGly proteomics, APEX2, proxiity biotinylation, CNN2

Christian Behrends
contact affiliation	Munich Cluster of Systems Neurology (SyNergy), LMU Munich, Germany
contact email	christian.behrends@mail03.med.uni-muenchen.de
lab head
Christian Behrends
contact affiliation	SyNergy, LMU München
contact email	christian.behrends@mail03.med.uni-muenchen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/06/PXD029926

PRIDE project URI

• PRIDE
  1. PXD029926
     1. Label: PRIDE project
     2. Name: Lysosomal damage proteomics in HeLa cells