PXD029858

PXD029858 is an original dataset announced via ProteomeXchange.

Title	Roles of USP2/E2F4 axis in autophagic machinery essential for cancer progression
Description	We investigated the potential proteins degraded by E2F4-induced autophagy via quantitative proteomics. To gain insight into protein partner essential for E2F4 stability, co-immunoprecipitation and mass spectrometry assays were performed.
HostingRepository	iProX
AnnounceDate	2021-11-19
AnnouncementXML	Submission_2023-03-13_00:10:54.179.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qiangsong Tong
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 5600; Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-11-21 20:47:39	ID requested
1	2022-11-29 20:06:10	announced
⏵ 2	2023-03-13 00:10:55	announced	2023-03-13: Update publication information.

Xiao W, Wang J, Wang X, Cai S, Guo Y, Ye L, Li D, Hu A, Jin S, Yuan B, Zhou Y, Li Q, Tong Q, Zheng L, Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression. Autophagy, 18(11):2615-2635(2022) [pubmed]

submitter keyword: E2F4, USP2

Qiangsong Tong
contact affiliation	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
contact email	qs_tong@hotmail.com
lab head
Qiangsong Tong
contact affiliation	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
contact email	qs_tong@hotmail.com
dataset submitter

iProX dataset URI