PXD029640

PXD029640 is an original dataset announced via ProteomeXchange.

Title	Quantitative Proteomics Reveal the Protective Effects of CuraUltra Against Alzheimer’s Disease via Modulating the Expression of Synapse-associated Proteins in Mouse Model
Description	To identify the potential molecular mechanism responsible for the effect on CuraUltra treatment, label-free quantitative proteomics by tandem mass spectrometry (LC-MS / MS) were performed, which provides in depth characterization of protein profile changes . Critical altered proteins were validated by qPCR and Western blot.
HostingRepository	iProX
AnnounceDate	2021-11-10
AnnouncementXML	Submission_2022-10-13_19:34:21.653.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qianqian Huang
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	6x(13)C labeled L-lysine
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2021-11-09 22:43:06	ID requested
1	2021-11-09 22:44:24	announced
⏵ 2	2022-10-13 19:34:23	announced	2022-10-14: Update publication information.

Huang Q, Zhang C, Qu S, Dong S, Ma Q, Hao Y, Liu Z, Wang S, Zhao H, Shi Y, Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer's Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway. Front Pharmacol, 13():817213(2022) [pubmed]

submitter keyword: mouse , Hippocampus , Tissue , LC - MSMS

Yuanyuan Shi
contact affiliation	Shenzhen Research Institute, Beijing University of Chinese Medicine, Shenzhen, China
contact email	yshi@bucm.edu.cn
lab head
Qianqian Huang
contact affiliation	Third Affiliated Hospital, Beijing University of Chinese Medicine, Beijing, China
contact email	huangqianqian110@163.com
dataset submitter

iProX dataset URI