PXD029483

PXD029483 is an original dataset announced via ProteomeXchange.

Title	Targeted proteomic validation of dysregulated proteins in liver tissue of Labeo rohita after Aeromonas hydrophila infection
Description	Aeromonas hydrophila (Ah) is an opportunistic Gram-negative bacterium and a serious global pathogen causing Motile Aeromonas Septicaemia (MAS) in fish and many other vertebrates. This study aimed at identifying the cellular proteins and processes altered by Ah infection in liver tissue of Labeo rohita, an important aquaculture species. Discovery based proteomics data could identify a panel of differentially expressed proteins (DEPs) between Control and AH condition (Ah infected group). Protein abundance changes in a few selected DEPs was then validated using Selected reaction monitoring (SRM) approach.
HostingRepository	PanoramaPublic
AnnounceDate	2023-05-02
AnnouncementXML	Submission_2023-05-02_09:08:40.586.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	supported by repository but incomplete data and/or metadata
PrimarySubmitter	Mehar Un Nissa
SpeciesList	scientific name: Labeo rohita; NCBI TaxID: 84645;
ModificationList	Carbamidomethyl; Label:13C(6)15N(2)
Instrument	TSQ Altis

Revision	Datetime	Status	ChangeLog Entry
0	2021-11-01 09:22:18	ID requested
⏵ 1	2023-05-02 09:08:41	announced

Nissa MU, Pinto N, Ghosh B, Singh U, Goswami M, Srivastava S, Proteomic analysis of liver tissue reveals Aeromonas hydrophila infection mediated modulation of host metabolic pathways in Labeo rohita. J Proteomics, 279():104870(2023) [pubmed]

submitter keyword: Aeromonas hydrophila, Liver proteomics, mass spectrometry, rohu, SRM

Sanjeeva Srivastava
contact affiliation	Biosciences and Bioengineering Department, IIT Bombay
contact email	sanjeeva@iitb.ac.in
lab head
Mehar Un Nissa
contact affiliation	Biosciences and Bioengineering Department, IIT Bombay
contact email	kohlimeharunnissa@gmail.com
dataset submitter

Panorama Public dataset URI