PXD029450

PXD029450 is an original dataset announced via ProteomeXchange.

Title	SCN Proteomic Study:electroacupuncture induced circadian control in Suprachiasmatic Nucleus
Description	Recent reports highlight phosphorylation as a major role in the regulation of sleep-wake cycles, to a lesser extent, the phosphoproteome in Suprachiasmatic Nucleus (SCN) is not well understood. We use multiplex tandem mass tag (TMT) - labelling coupled with liquid chromatography-mass spectrometry (LC-MS) to study the rhythmic regulatory effects of electroacupuncture(EA) at different times in constant darkness and the mechanism of EA mediated SCN protein phosphorylation. We applied the mass spectrometry-based phosphoproteome to explore the molecular characteristics of EA-induced phosphorylation modification in the SCN.
HostingRepository	iProX
AnnounceDate	2021-10-31
AnnouncementXML	Submission_2022-10-13_19:32:27.695.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dingjun Cai
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	phosphorylated residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2021-10-31 20:54:45	ID requested
1	2021-10-31 20:56:10	announced
⏵ 2	2022-10-13 19:32:28	announced	2022-10-14: Update publication information.

Lu X, Zhou M, Liu N, Zhang C, Zhao Z, Cai D, Synaptic Protein Phosphorylation Networks Are Associated With Electroacupuncture-Induced Circadian Control in the Suprachiasmatic Nucleus. Front Genet, 12():762557(2021) [pubmed]

submitter keyword: phosphorylation, mass spectrometry, electro-acupuncture, circadian rhythm, suprachiasmatic nucleus

Dingjun Cai
contact affiliation	Acupuncture and Chronobiology Key Laboratory of Sichuan Province, Chengdu, China.
contact email	djcai@cdutcm.edu.cn
lab head
Dingjun Cai
contact affiliation	Chengdu University of Traditional Chinese Medicine, Chengdu, China.
contact email	djcai@cdutcm.edu.cn
dataset submitter

iProX dataset URI