PXD029436

PXD029436 is an original dataset announced via ProteomeXchange.

Title	The preclinical evaluation of a second-generation antivenom for treating snake envenoming in India
Description	In this study, by employing chromatographic purification of the bulk, we have significantly enhanced the preclinical performance of the conventional Indian antivenom product. The effectiveness of the test batches of this ‘second-generation’ antivenom was evaluated using a variety of in vitro and in vivo preclinical assays, including venom recognition and toxicity and pathology neutralisation. The outcomes of these experiments demonstrated the significantly superior performance of the purified product over all other major commercial Indian antivenoms.
HostingRepository	PRIDE
AnnounceDate	2022-05-25
AnnouncementXML	Submission_2022-05-25_09:23:48.783.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kartik Sunagar
SpeciesList	scientific name: Equus caballus; NCBI TaxID: 9796;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2021-10-29 06:36:34	ID requested
⏵ 1	2022-05-25 09:23:49	announced

Attarde S, Iyer A, Khochare S, Shaligram U, Vikharankar M, Sunagar K, The Preclinical Evaluation of a Second-Generation Antivenom for Treating Snake Envenoming in India. Toxins (Basel), 14(3):(2022) [pubmed]

submitter keyword: Antivenoms, second-generation antivenoms, snakebite

Dr. Kartik Sunagar
contact affiliation	Assistant Professor, Evolutionary Venomics Lab, Center for Ecological Sciences, Indian Institute of Science, Bangalore, India
contact email	ksunagar@iisc.ac.in
lab head
Kartik Sunagar
contact affiliation	Assistant Professor, Centre for Ecological Sciences, Indian Institute of Science, Bangalore 560012, Karnataka, India.
contact email	ksunagar@iisc.ac.in
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD029436

PRIDE project URI

• PRIDE
  1. PXD029436
     1. Label: PRIDE project
     2. Name: The preclinical evaluation of a second-generation antivenom for treating snake envenoming in India