PXD029435 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteome and phosphoproteome analysis of autophagy deficient ATG5flox:CamKII-Cre and ATG5flox:VGAT-Cre conditional knockout mice |
Description | The experiment was performed to find selective targets of autophagy in different subtypes of neurons. Therefore, brain tissue of conditional knockout mice lacking autophagy protein ATG5 in inhibitory or excitatory neurons was used. Cortices (ATG5flox:CamKII-Cre) / striata (ATG5flox:VGAT-Cre) of mice were mixed with lys6 labeled brain lysates as internal controls between the samples. Samples were measured by LC-MS/MS and resulting H/L ratios were used to quantify proteomic and phosphoproteomic changes. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_07:35:32.144.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Frederik Tellkamp |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | phosphorylated residue |
Instrument | Orbitrap Eclipse |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-10-29 05:19:40 | ID requested | |
1 | 2022-11-15 06:38:41 | announced | |
⏵ 2 | 2023-11-14 07:35:35 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
submitter keyword: ATG5, neurons,autophagy, brain |
Contact List
Natalia L Kononenko |
contact affiliation | CECAD Excellence Center & Center for Physiology, Medical Faculty, University of Cologne, Germany |
contact email | n.kononenko@uni-koeln.de |
lab head | |
Frederik Tellkamp |
contact affiliation | University of Cologne, Department of Biology, Institute for Genetics |
contact email | frederik.tellkamp@uni-koeln.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/11/PXD029435 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD029435
- Label: PRIDE project
- Name: Proteome and phosphoproteome analysis of autophagy deficient ATG5flox:CamKII-Cre and ATG5flox:VGAT-Cre conditional knockout mice