PXD029328

PXD029328 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic analysis of adipose tissue revealing differentially abundant proteins in highly efficient mid-lactating cows
Description	The current situation of rising demand for animal products and sustainable resource usage, improving nutrient utilization efficiency in dairy cows is an important task. Understanding the biology of feed efficiency in dairy cows enables for the development of markers that may be used to identify and choose the best animals for animal production. Thus in this study, ten Holstein cows were evaluated for feed efficiency and adipose tissue samples from five high efficient and five low efficient dairy cows were collected for protein extraction, digestion and data were analyzed for differential abundant proteins enriched in feed efficiency pathways. Among the identified peptides, we found 110 DAPs and two protein networks significantly related to feed efficiency. Among the relative mRNA expression of genes involved in energy metabolism including transcription/translation (STAT2, DDX39A and RBM39) or protein transport (ITGAV), only RBM39 showed significant decrease in high efficient dairy cows. The findings presented here confirmed the Transferrin upregulated in pathways including acute phase response signaling, LXR/RXR activation, FXR/RXR activation of high efficient dairy cows supporting that these pathways are related to feed efficiency in dairy cows.
HostingRepository	PRIDE
AnnounceDate	2022-08-12
AnnouncementXML	Submission_2022-08-11_22:28:12.736.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yishai Levin
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-10-25 02:42:40	ID requested
⏵ 1	2022-08-11 22:28:13	announced

Publication List

Ben Meir YA, Daddam JR, Kra G, Kamer H, Portnick Y, Levin Y, Zachut M, Proteomic analysis of adipose tissue revealing differentially abundant proteins in highly efficient mid-lactating dairy cows. Sci Rep, 12(1):9721(2022) [pubmed]

Ben Meir YA, Daddam JR, Kra G, Kamer H, Portnick Y, Levin Y, Zachut M, Proteomic analysis of adipose tissue revealing differentially abundant proteins in highly efficient mid-lactating dairy cows. Sci Rep, 12(1):9721(2022) [pubmed]

Keyword List

submitter keyword: Bovine milk, lactating, proteomics, cows

submitter keyword: Bovine milk, lactating, proteomics, cows

Contact List

Maya Zachut
contact affiliation	Department of Ruminant Science, Institute of Animal Sciences, Agricultural Research Organization, Volcani Center, Israel
contact email	mayak@volcani.agri.gov.il
lab head
Yishai Levin
contact affiliation	Weizmann Institute of Science, Israel
contact email	yishai.levin@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD029328
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD029328

PRIDE project URI

Repository Record List

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