PXD029264 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Perception of a conserved family of plant signaling peptides by the receptor kinase HSL3 |
Description | Plant genomes encode hundreds of secreted peptides; however, relatively few have been characterised. We report here an uncharacterised, stress-induced family of plant signalling peptides, which we call CTNIPs. Based on the role of the common co-receptor BRASSINOSTEROID INSENSITIVE 1-ASSOCIATED KINASE 1 (BAK1) in CTNIP-induced responses, we identified the orphan receptor kinase HAESA-LIKE 3 (HSL3) as the CTNIP receptor via a proteomics approach. CTNIP binding, ligand-triggered complex formation with BAK1, and induced downstream responses all involve HSL3. Notably, the HSL3-CTNIP signalling module is evolutionary ancient, predating the divergence of extant angiosperms. Definition of this signalling module will help establish its physiological role and provides a resource to understand further receptor-ligand co-evolution. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-07 |
AnnouncementXML | Submission_2024-10-07_10:57:09.271.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD029264 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | FRank Menke |
SpeciesList | scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-10-21 05:07:42 | ID requested | |
⏵ 1 | 2024-10-07 10:57:10 | announced | |
Publication List
10.6019/PXD029264; |
10.7554/elife.74687; |
Rhodes J, Roman AO, Bjornson M, Brandt B, Derbyshire P, Wyler M, Schmid MW, Menke FLH, Santiago J, Zipfel C, Perception of a conserved family of plant signalling peptides by the receptor kinase HSL3. Elife, 11():(2022) [pubmed] |
Keyword List
submitter keyword: receptor, immunity, arabidopsis |
Contact List
Frank L.H. Menke |
contact affiliation | The Sainsbury Laboratory |
contact email | frank.menke@tsl.ac.uk |
lab head | |
FRank Menke |
contact affiliation | the Sainsbury laboratory |
contact email | Frank.Menke@tsl.ac.uk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD029264
- Label: PRIDE project
- Name: Perception of a conserved family of plant signaling peptides by the receptor kinase HSL3