PXD029245

PXD029245 is an original dataset announced via ProteomeXchange.

Title	Deciphering Black Extrinsic Tooth Stains composition in Children using metaproteomics
Description	The present study focuses on the use of a metaproteomic approach to analyse Black Extrinsic Tooth Stains, a specific type of pigmented extrinsic substance, in a cohort of 96 Children. Metaproteomics is a powerful emerging technology that successfully enabled human protein and bacterial identification of this specific dental biofilm using mass spectrometry. 1600 bacterial proteins were identified in black stains (BS) samples and 2058 proteins in dental plaque (DP) samples whereas 607 and 582 human proteins identified in (BS and DP, respectively). 132 genera bacteria in black stains and dental plaque were identified using phylopeptidomic analysis, showing prevalence of Rothia, Kingella, Nesseria and Pseudopropionibatcterium in black stains samples. We additionally confirmed the metaproteomic approach by performing 16S rRNA. In this work, we showed an interesting diversity of the microbiota and proteome including significant difference between Black stain and dental plaque samples.
HostingRepository	PRIDE
AnnounceDate	2024-07-25
AnnouncementXML	Submission_2024-07-25_13:04:06.730.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jerome Vialaret
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	maXis

Revision	Datetime	Status	ChangeLog Entry
0	2021-10-20 08:12:37	ID requested
⏵ 1	2024-07-25 13:04:07	announced

10.1021/ACSOMEGA.1C04770;

submitter keyword: saliva, dental plaque, oral pathology, metaproteomics

HIRTZ Christophe
contact affiliation	Lab's head of proteomics platform, Montpellier hospital
contact email	c-hirtz@chu-montpellier.fr
lab head
Jerome Vialaret
contact affiliation	CHU Montpellier
contact email	j-vialaret@chu-montpellier.fr
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD029245
     1. Label: PRIDE project
     2. Name: Deciphering Black Extrinsic Tooth Stains composition in Children using metaproteomics