PXD029129

PXD029129 is an original dataset announced via ProteomeXchange.

Title	Proteome of neutrophils upon migration towards inflamed synovial fluid
Description	Analysis of neutrophil proteomic alterations induced by migration towards inflamed joints in juvenile idiopathic arthritis (JIA). In this experiment neutrophil proteomes were investigated after migration towards JIA synovial fluid in an in vitro model of a synovial membrane, compared to neutrophils incubated in synovial fluid without migration. The migration model consisted of transwell inserts with human knee synoviocytes on the undersides and HMEC endothelial cells on the insides, placed in wells containing medium with 10 % JIA synovial fluid.
HostingRepository	PRIDE
AnnounceDate	2022-02-15
AnnouncementXML	Submission_2022-02-15_11:47:09.133.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD029129
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Charlotte Welinder
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2021-10-14 07:59:22	ID requested
⏵ 1	2022-02-15 11:47:09	announced

Arve-Butler S, Mossberg A, Schmidt T, Welinder C, Yan H, Berthold E, Kr, ó, l P, Kahn R, Neutrophils Lose the Capacity to Suppress T Cell Proliferation Upon Migration Towards Inflamed Joints in Juvenile Idiopathic Arthritis. Front Immunol, 12():795260(2021) [pubmed]

submitter keyword: Neutrophil, migration, synovial fluid, juvenile idiopathic arthritis

Sabine Caroline Arve-Butler
contact affiliation	Dept of Rheumatology, Clinical Science Lund, Lund university, Sweden
contact email	Sabine.arve-butler@med.lu.se
lab head
Charlotte Welinder
contact affiliation	Dept. of Oncology, Clinical Sciences, Lund University, 221 85 Lund, Sweden
contact email	charlotte.welinder@med.lu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD029129

PRIDE project URI

• PRIDE
  1. PXD029129
     1. Label: PRIDE project
     2. Name: Proteome of neutrophils upon migration towards inflamed synovial fluid