PXD029079

PXD029079 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Circuit-wide Proteomics Profiling Reveals Brain Region-specific Protein Signatures in the WKY Rats with Endogenous Depression
Description	Major depressive disorder (MDD) is considered as a neural circuit-based polygene syndrome that is mainly triggered by genetic susceptibility and stress factors. The present study employed the Wistar Kyoto (WKY) rat as an animal model with endogenous depression to further investigate the molecular basis of its genetic susceptibility to depression by performing quantitative protemoics analyses of the medial prefrontal cortex (mPFC), nucleus accumbens (NAc), and hippocampus (Hip), respectively.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:41:34.190.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jiangfeng Liao
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-10-12 07:53:41	ID requested
1	2022-10-13 06:03:36	announced
⏵ 2	2023-11-14 07:41:38	announced	2023-11-14: Updated project metadata.

Publication List

Liao J, Mi X, Zeng G, Wei Y, Dai X, Ye Q, Chen X, Zhang J, Circuit-wide proteomics profiling reveals brain region-specific protein signatures in the male WKY rats with endogenous depression. J Affect Disord, 320():98-107(2023) [pubmed]

Liao J, Mi X, Zeng G, Wei Y, Dai X, Ye Q, Chen X, Zhang J, Circuit-wide proteomics profiling reveals brain region-specific protein signatures in the male WKY rats with endogenous depression. J Affect Disord, 320():98-107(2023) [pubmed]

Keyword List

submitter keyword: Depression
Wistar Kyoto rats
Proteomics
Medial prefrontal cortex
Nucleus accumbens
Hippocampus

submitter keyword: Depression

Wistar Kyoto rats

Proteomics

Medial prefrontal cortex

Nucleus accumbens

Hippocampus

Contact List

Xiaochun Chen
contact affiliation	Department of Neurology, Fujian Medical University Union Hospital
contact email	chenxc998@fjmu.edu.cn
lab head
Jiangfeng Liao
contact affiliation	Fujian Medical University
contact email	jf.liao@qq.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD029079
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD029079

PRIDE project URI

Repository Record List

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