PXD029066
PXD029066 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Comparative salivary proteomics of people with different blood glucose levels |
| Description | To evaluate the effect of glycemic control status in middle-aged and elderly individuals with type 2 diabetes mellitus (T2DM) on oral proteomic by liquid chromatography tandem mass spectrometry (LC-MS/MS). Twenty-four individuals who met the criteria were included and divided into a well-controlled group and a poorly-controlled group according to their glycated hemoglobin levels. The two groups were matched in age, gender and clinical parameters. After unstimulated whole saliva samples were collected, LC-MS/MS technique in data independent acquisition (DIA) mode was used to detect the proteins in samples. In addition, we compared the differentially expressed proteins between groups with different glycemic levels in saliva. Finally, we performed functional annotation and enrichment analysis of proteins. |
| HostingRepository | iProX |
| AnnounceDate | 2021-10-11 |
| AnnouncementXML | Submission_2022-10-13_21:07:29.056.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Shuyuan Jia |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2021-10-11 21:31:46 | ID requested | |
| 1 | 2021-11-22 19:19:47 | announced | |
| ⏵ 2 | 2022-10-13 21:07:29 | announced | 2022-10-14: Update publication information. |
Publication List
| Jia SY, Zhang YL, Sun XY, Yuan C, Zheng SG, Impact of the Glycemic Level on the Salivary Proteome of Middle-Aged and Elderly People With Type 2 Diabetes Mellitus: An Observational Study. Front Mol Biosci, 8():790091(2021) [pubmed] |
Keyword List
| submitter keyword: Quantitative proteomics, saliva, blood glucose |
Contact List
| Shuguo Zheng | |
|---|---|
| contact affiliation | Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases |
| contact email | kqzsg86@bjmu.edu.cn |
| lab head | |
| Shuyuan Jia | |
| contact affiliation | Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases |
| contact email | jiashuyuancindy@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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