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PXD029034

PXD029034 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleA Membrane-Permeable and Immobilized Metal Affinity Chromatography (IMAC)-Enrichable Cross-Linking Reagent to Advance In Vivo Cross-Linking Mass Spectrometry
DescriptionWe developed a novel membrane-permeable and IMAC-enrichable cross-linker tBu-PhoX. Applying our optimized in vivo XL-MS pipeline, we revealed protein interaction landscape of intact human cells.
HostingRepositoryPRIDE
AnnounceDate2022-01-11
AnnouncementXMLSubmission_2022-01-11_02:50:15.635.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPin-Lian Jiang
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-10-10 22:56:28ID requested
12022-01-11 02:50:16announced
Publication List
Jiang PL, Wang C, Diehl A, Viner R, Etienne C, Nandhikonda P, Foster L, Bomgarden RD, Liu F, Vivo Cross-Linking Mass Spectrometry. Angew Chem Int Ed Engl, 61(12):e202113937(2022) [pubmed]
Keyword List
submitter keyword: Mass spectrometry, protein-protein interactions, crosslinking, proteomics, protein structures
Contact List
Fan Liu
contact affiliationLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)
contact emailFLiu@fmp-berlin.de
lab head
Pin-Lian Jiang
contact affiliationLeibniz-Forschungsinstitut für Molekulare Pharmakologie
contact emailjiang@fmp-berlin.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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