PXD028998

PXD028998 is an original dataset announced via ProteomeXchange.

Title	Hippocampal proteomics analysis of marginal zinc deficiency
Description	Zinc is an essential trace element that is closely related to learning and memory ability. The hippocampus plays an important role in learning and memory and has the highest zinc concentration in the brain. Severe zinc deficiency (zinc-deprived diet) significantly alter hippocampal protein expression and impair learning and memory abilities. However, no study has investigated the effects of marginal zinc deficiency (low zinc diet) on hippocampal proteins and learning and memory abilities. In this study, the rat model after 4 and 8 weeks of feeding with low zinc diet was first used to identify and quantify the hippocampal proteins of low zinc rats by high-thoughput proteomics technology. Explore the changes of hippocampus proteome patterns after 4 and 8 weeks of feeding with low zinc diet were compared with those in control rats.
HostingRepository	iProX
AnnounceDate	2021-10-04
AnnouncementXML	Submission_2023-12-21_20:39:59.006.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Maoqing Wang
SpeciesList	scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2021-10-07 20:08:00	ID requested
⏵ 1	2023-12-21 20:39:59	announced

Sun Y, Zhao J, Song X, Sun Z, Zhang R, Zhong J, Huang X, Dong Y, Yu Q, Dong F, Li Z, Fan L, Wang M, Peng C, Wang F, Effects of marginal zinc deficiency on learning and memory ability after birth. Food Funct, 13(13):7204-7214(2022) [pubmed]

submitter keyword: Marginal zinc deficiency, hippocampus proteomics,TMT isobaric labeling

Maoqing Wang
contact affiliation	National Key Disciplines of Nutrition and Food Hygiene, Department of Nutrition and Food Hygiene, School of Public Health, Harbin Medical University, Harbin, China
contact email	wang_maoqing@126.com
lab head
Maoqing Wang
contact affiliation	National Key Disciplines of Nutrition and Food Hygiene, Department of Nutrition and Food Hygiene, School of Public Health, Harbin Medical University, Harbin, China
contact email	wang_maoqing@126.com
dataset submitter

iProX dataset URI