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PXD028976

PXD028976 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of human SKBR3/HER2+ breast cancer glycosylated cell-surface proteins
DescriptionThe plasma membrane proteome resides at the interface between the extra- and intra-cellular environment and through its various roles in signal transduction, immune recognition, nutrient transport, and cell-cell and cell-matrix interactions plays a critical role in determining the fate of a cell. The objective of this study was to characterize the cell-membrane proteome of SKBR3/HER2+ breast cancer cells by using mass spectrometry detection, to advance the understanding of biological triggers that sustain aberrant cell survival, proliferation, and development of resistance to therapeutic drugs.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:53:40.022.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterArba Karcini
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-10-07 00:26:26ID requested
12022-07-11 07:34:21announced
22023-11-14 08:53:40announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: cancer, glycoproteins, cell-surface,SKBR3 cells
Contact List
Iulia M. Lazar
contact affiliationVirginia Tech, Biological Sciences
contact emailmalazar@vt.edu
lab head
Arba Karcini
contact affiliationVirginia Tech
contact emailakarcini@vt.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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