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PXD028960

PXD028960 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIn vivo BioID Mouse heart masspec data
DescriptionCardiac excitation-contraction (E-C) coupling requires dyads, the nanoscopic microdomains formed adjacent to Z-lines by apposition of transverse (T)-tubules and junctional sarcoplasmic reticulum (jSR). Disruption of dyad architecture and function are common features of diseased cardiomyocytes. However, little is known about the mechanisms that modulate dyad organization during cardiac homeostasis and disease. Here, we used proximity proteomics in intact, living hearts to identify proteins enriched near dyads.
HostingRepositoryPRIDE
AnnounceDate2022-02-21
AnnouncementXMLSubmission_2022-02-21_09:21:22.122.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD028960
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterFujian Lu
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListbiotinylated residue
InstrumentLTQ; LTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-10-06 04:19:08ID requested
12022-02-21 09:21:22announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Mouse hearts, BioID, RyR2, Ca signaling
Contact List
William T. Pu
contact affiliationDepartment of Cardiology Boston Children's Hospital
contact emailwilliam.pu@cardio.chboston.org
lab head
Fujian Lu
contact affiliationBoston Children's Hospital
contact emailfujian.lu@childrens.harvard.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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