PXD028930

PXD028930 is an original dataset announced via ProteomeXchange.

Title	Proteomic Analysis on Paraffine-Archived Melanoma
Description	The discovery of novel protein biomarkers in melanoma is crucial. Our introduction of formalin-fixed paraffin embedded (FFPE) tumor protocol provides new opportunities to understand the progression of melanoma and open the possibility to screen tens of thousands of FFPE samples deposited in tumor biobanks and available at hospital pathology departments. In our retrospective pilot study, 90 FFPE samples from 77 patients were processed. Differential quantitative protein expression was performed by high resolution mass spectrometry. The protein expression profiles were correlated with the standardized dataset of histopathologic analysis, and longitudinal therapeutical meta-data.
HostingRepository	PRIDE
AnnounceDate	2022-02-17
AnnouncementXML	Submission_2022-02-17_00:27:50.310.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lazaro H. Betancourt Nunez
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2021-10-04 10:02:19	ID requested
⏵ 1	2022-02-17 00:27:51	announced

Szadai L, Velasquez E, Szeitz B, Almeida NP, Domont G, Betancourt LH, Gil J, Marko-Varga M, Oskolas H, J, á, nosi Á J, Boyano-Ad, á, nez MDC, Kem, é, ny L, Baldetorp B, Malm J, Horvatovich P, Sz, á, sz AM, N, é, meth IB, Marko-Varga G, Deep Proteomic Analysis on Biobanked Paraffine-Archived Melanoma with Prognostic/Predictive Biomarker Read-Out. Cancers (Basel), 13(23):(2021) [pubmed]

ProteomeXchange project tag: CPTAC Consortium

submitter keyword: metastatic melanoma, immunotherapy targeted therapy responder, prognostic and predictive biomarkers, outcome and survival by protein expression, proteomics

Gyorgy Marko-Varga
contact affiliation	Clinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University
contact email	gyorgymarkovarga@hotmail.com
lab head
Lazaro H. Betancourt Nunez
contact affiliation	Lund University
contact email	lazaro_hiram.betancourt_nunez@med.lu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD028930

PRIDE project URI

• PRIDE
  1. PXD028930
     1. Label: PRIDE project
     2. Name: Proteomic Analysis on Paraffine-Archived Melanoma