PXD028917

PXD028917 is an original dataset announced via ProteomeXchange.

Title	Mouse sperm protamine mass spectrometry
Description	Conventional dogma presumes that protamine-mediated DNA compaction in sperm is achieved by passive electrostatics between DNA and the arginine-rich core of protamines. However, phylogenetic analysis reveals several non-arginine residues that are conserved within, but not across, species. The functional significance of these residues or post-translational modifications are poorly understood. In this experiment, we investigated the presence of post-translational modifications on mouse protamine 1 to begin to dissect their function in vivo.
HostingRepository	PRIDE
AnnounceDate	2023-05-17
AnnouncementXML	Submission_2023-05-17_12:22:52.511.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD028917
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	LindsayMoritz
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monomethylated residue; phosphorylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-10-04 10:00:35	ID requested
⏵ 1	2023-05-17 12:22:52	announced

10.6019/PXD028917;

submitter keyword: sperm,protamine, chromatin

SueHammoud
contact affiliation	Department of Human Genetics, University of Michigan, USA
contact email	hammou@med.umich.edu
lab head
LindsayMoritz
contact affiliation	University of Michigan
contact email	moritzle@umich.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD028917

PRIDE project URI

• PRIDE
  1. PXD028917
     1. Label: PRIDE project
     2. Name: Mouse sperm protamine mass spectrometry