PXD028917 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mouse sperm protamine mass spectrometry |
Description | Conventional dogma presumes that protamine-mediated DNA compaction in sperm is achieved by passive electrostatics between DNA and the arginine-rich core of protamines. However, phylogenetic analysis reveals several non-arginine residues that are conserved within, but not across, species. The functional significance of these residues or post-translational modifications are poorly understood. In this experiment, we investigated the presence of post-translational modifications on mouse protamine 1 to begin to dissect their function in vivo. |
HostingRepository | PRIDE |
AnnounceDate | 2023-05-17 |
AnnouncementXML | Submission_2023-05-17_12:22:52.511.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD028917 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | LindsayMoritz |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | monomethylated residue; phosphorylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-10-04 10:00:35 | ID requested | |
⏵ 1 | 2023-05-17 12:22:52 | announced | |
Publication List
Keyword List
submitter keyword: sperm,protamine, chromatin |
Contact List
SueHammoud |
contact affiliation | Department of Human Genetics, University of Michigan, USA |
contact email | hammou@med.umich.edu |
lab head | |
LindsayMoritz |
contact affiliation | University of Michigan |
contact email | moritzle@umich.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD028917
- Label: PRIDE project
- Name: Mouse sperm protamine mass spectrometry