PXD028832 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates metabolism and development via translation (Identification of m1A mRNA methyltransferase in nucleus by TMT11-LC-MS/MS) |
Description | m1A has long been known to be important in tRNA and rRNA, but we recently mapped many m1A sites in mRNA as well. m1A is found on the 5’ ends of genes, usually around the first splice site, but we have yet to understand how it effects transcript fate. Identifying the methyltransferase would be a major first step towards understanding m1A function. |
HostingRepository | PRIDE |
AnnounceDate | 2021-11-30 |
AnnouncementXML | Submission_2021-11-30_14:44:34.687.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Zuo-Fei Yuan |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-09-29 01:33:37 | ID requested | |
⏵ 1 | 2021-11-30 14:44:35 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Proteomics, m1A mRNA methyltransferase, METTL5, TRMT112, mass spectrometry |
Contact List
Haiyan Tan |
contact affiliation | Center for Proteomics and Metabolomics St. Jude Children's Research Hospital |
contact email | Haiyan.Tan@stjude.org |
lab head | |
Zuo-Fei Yuan |
contact affiliation | St. Jude Children's Research Hospital |
contact email | zuo-fei.yuan@stjude.org |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
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[ - ]
- PRIDE
- PXD028832
- Label: PRIDE project
- Name: The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates metabolism and development via translation (Identification of m1A mRNA methyltransferase in nucleus by TMT11-LC-MS/MS)