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PXD028813

PXD028813 is an original dataset announced via ProteomeXchange.

Dataset Summary
Titlep300 acetylates Ub and linear Ub dimers
DescriptionIn this project we present the identification of in vitro acetylation of Ub by the acetyltransferase p300. Free monomeric Ub or M1-linked linear Ub dimers (diUb) were incubated in vitro with p300 in presence or absence of acetyl-Coenzyme A (AcCoA). For identification of the acetylation status of the respective Ub variants parallel reaction monitoring (PRM), a targeted-MS approach, was used.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_07:54:34.411.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSimon Kienle
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-09-28 09:41:33ID requested
12022-10-13 19:03:48announced
22023-11-14 07:54:35announced2023-11-14: Updated project metadata.
Publication List
Kienle SM, Schneider T, Stuber K, Globisch C, Jansen J, Stengel F, Peter C, Marx A, Kovermann M, Scheffner M, Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function. Nat Commun, 13(1):5435(2022) [pubmed]
Keyword List
submitter keyword: acetylation, acetyltransferase p300,Ub
Contact List
Prof. Dr. Martin Scheffner
contact affiliationDepartment of Biology, University of Konstanz, Germany
contact emailAG.Scheffner@uni-konstanz.de
lab head
Simon Kienle
contact affiliationUniversity of Konstanz
contact emailSimon.Kienle@uni-konstanz.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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