PXD028804

PXD028804 is an original dataset announced via ProteomeXchange.

Title	Proteomic identification of an endogenous synaptic SUMOylome in the developing rat brain
Description	Synapses are highly specialized structures that interconnect neurons to form functional networks dedicated to neuronal communication. During brain development, synapses undergo activity-dependent rearrangements leading to both structural and functional changes. Many molecular processes are involved in this regulation, including post-translational modifications by the Small Ubiquitin-like MOdifier SUMO. To get a wider view of the panel of endogenous synaptic SUMO-modified proteins in the mammalian brain, we combined subcellular fractionation of rat brains at the post-natal day 14 with denaturing immunoprecipitation using SUMO2/3 antibodies and tandem mass spectrometry analysis.
HostingRepository	PRIDE
AnnounceDate	2021-11-25
AnnouncementXML	Submission_2021-11-25_09:35:41.907.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Carole Gwizdek
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-09-28 03:20:46	ID requested
⏵ 1	2021-11-25 09:35:42	announced

Dataset with its publication pending

submitter keyword: synapse, post-translational modification, SUMO, developping rat brain

Stéphane MARTIN
contact affiliation	Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur, Centre National de la Recherche Scientifique, France
contact email	martin@ipmc.cnrs.fr
lab head
Carole Gwizdek
contact affiliation	Université Côte d'Azur, Centre National de la Recherche Scientifique, Institut de Pharmacologie Moléculaire et Cellulaire
contact email	gwizdek@ipmc.cnrs.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD028804

PRIDE project URI

• PRIDE
  1. PXD028804
     1. Label: PRIDE project
     2. Name: Proteomic identification of an endogenous synaptic SUMOylome in the developing rat brain