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PXD028804 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic identification of an endogenous synaptic SUMOylome in the developing rat brain
DescriptionSynapses are highly specialized structures that interconnect neurons to form functional networks dedicated to neuronal communication. During brain development, synapses undergo activity-dependent rearrangements leading to both structural and functional changes. Many molecular processes are involved in this regulation, including post-translational modifications by the Small Ubiquitin-like MOdifier SUMO. To get a wider view of the panel of endogenous synaptic SUMO-modified proteins in the mammalian brain, we combined subcellular fractionation of rat brains at the post-natal day 14 with denaturing immunoprecipitation using SUMO2/3 antibodies and tandem mass spectrometry analysis.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterCarole Gwizdek
SpeciesList scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-09-28 03:20:46ID requested
12021-11-25 09:35:42announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: synapse, post-translational modification, SUMO, developping rat brain
Contact List
Stéphane MARTIN
contact affiliationInstitut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur, Centre National de la Recherche Scientifique, France
contact emailmartin@ipmc.cnrs.fr
lab head
Carole Gwizdek
contact affiliationUniversité Côte d'Azur, Centre National de la Recherche Scientifique, Institut de Pharmacologie Moléculaire et Cellulaire
contact emailgwizdek@ipmc.cnrs.fr
dataset submitter
Full Dataset Link List
Dataset FTP location
PRIDE project URI
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