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PXD028693

PXD028693 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuh7 cells proteoic analysis withtomatidine treatment at 6 and 16 hours post-treatment
DescriptionTomatidine, a natural steroidal alkaloid from unripe green tomatoes has been shown to exhibit many health benefits. We recently provided in vitro evidence that tomatidine reduces the infectivity of Dengue virus (DENV) and Chikungunya virus (CHIKV), two medically important arthropod-borne human infections for which no treatment options are available. The objective of this mass spectrometry analysis was to determine possible proteomic changes in the human cell line Huh7 induced by tomatidine which may be indicative of the underlying antiviral activity of tomatidine.
HostingRepositoryPRIDE
AnnounceDate2021-11-18
AnnouncementXMLSubmission_2021-11-18_08:49:08.291.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBerit Troost-Kind
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-09-22 11:58:46ID requested
12021-11-18 08:49:08announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Huh7 cells, tomatidine
Contact List
Jolanda M. Smit
contact affiliationDepartment of Medical Microbiology and Infection Prevention, University of Groningen; University Medical Center Groningen; Groningen, the Netherlands
contact emailjolanda.smit@umcg.nl
lab head
Berit Troost-Kind
contact affiliationUniversity Medical Center Groningen
contact emailBerit.troost@yahoo.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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