PXD028467

PXD028467 is an original dataset announced via ProteomeXchange.

Title	The lysine acetylome in Vibrio mimicus
Description	In the present study, we performed the first global lysine acetylome in V. mimicus through a combination of highly sensitive immune-affinity purification and high-resolution LC−MS/MS, and identified 1097 lysine-acetylated sites on 582 proteins. Of the acetylated proteins, more than half were acetylated on one site. In the acetylome of V. mimicus, six significantly enriched motifs were identified and obtained including KacL, KacR, L(-2)KacL, LKacK, L(-7)EKac, and IEKac. In addition, bioinformatics results indicated that acetylated proteins participate in many different biological functions in V. mimicus, such as purine metabolism, ribosome, pyruvate metabolism, glycolysis / gluconeogenesis, TCA cycle, and so on. Moreover, 13 acetylated proteins were related to the virulence of V. mimicus.
HostingRepository	iProX
AnnounceDate	2021-09-14
AnnouncementXML	Submission_2022-11-11_01:20:21.948.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wanxin Li
SpeciesList	scientific name: Vibrio mimicus VM603; NCBI TaxID: 671074;
ModificationList	acetylated residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2021-09-14 19:02:37	ID requested
⏵ 1	2022-11-11 01:20:24	announced

Wang J, Pang H, Yin L, Zeng F, Wang N, Hoare R, Monaghan SJ, Li W, Jian J, . Front Microbiol, 13():816968(2022) [pubmed]

submitter keyword: Vibrio mimicus, lysine acetylation, acetylome, virulence

Huanying Pang
contact affiliation	Fisheries College of Guangdong Ocean University
contact email	phying1218@163.com
lab head
Wanxin Li
contact affiliation	School of Public Health, Fujian Medical University, Fuzhou
contact email	liwx2012@126.com
dataset submitter

iProX dataset URI