PXD028442
PXD028442 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic change in cerebrospinal fluid of neonatal sepsis |
Description | Neonatal infection and sepsis are common for preterm infants due to their immature immune system. Acute changes of proteins in the cerebrospinal fluid (CSF), potentially affect the immature brain of preterm neonates. In this study, collected human CSF samples were processed according to the enhanced filter-aided sample preparation (eFASP) protocol and run on a Dionex RSLC UPLC System coupled to an Orbitrap Fusion Lumos Mass Spectrometer. Protein annotation and quantification were carried out using MaxQuant (version 1.5.2.8) against the Uniprot database (homo sapiens, UP0000085640). |
HostingRepository | iProX |
AnnounceDate | 2021-09-09 |
AnnouncementXML | Submission_2022-10-19_20:38:34.608.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Shanshan Peng |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-09-09 19:44:07 | ID requested | |
1 | 2021-09-09 19:44:18 | announced | |
⏵ 2 | 2022-10-19 20:38:35 | announced | 2022-10-20: Update publication information. |
Publication List
Jiang PP, Peng SS, Pankratova S, Luo P, Zhou P, Chen Y, Proteins Involved in Synaptic Plasticity Are Downregulated in the Cerebrospinal Fluid of Infants With Clinical Sepsis Complicated by Neuroinflammation. Front Cell Neurosci, 16():887212(2022) [pubmed] |
Keyword List
submitter keyword: neonatal sepsis, cerebrospinal fluid, proteomics, meningitis |
Contact List
Pingping Jiang | |
---|---|
contact affiliation | Sun Yat-sen Univeristy |
contact email | jiangpp3@mail.sysu.edu.cn |
lab head | |
Shanshan Peng | |
contact affiliation | Sun Yat-sen University |
contact email | pengshsh6@mail2.sysu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |