PXD028442

PXD028442 is an original dataset announced via ProteomeXchange.

Title	Proteomic change in cerebrospinal fluid of neonatal sepsis
Description	Neonatal infection and sepsis are common for preterm infants due to their immature immune system. Acute changes of proteins in the cerebrospinal fluid (CSF), potentially affect the immature brain of preterm neonates. In this study, collected human CSF samples were processed according to the enhanced filter-aided sample preparation (eFASP) protocol and run on a Dionex RSLC UPLC System coupled to an Orbitrap Fusion Lumos Mass Spectrometer. Protein annotation and quantification were carried out using MaxQuant (version 1.5.2.8) against the Uniprot database (homo sapiens, UP0000085640).
HostingRepository	iProX
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2022-10-19_20:38:34.608.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shanshan Peng
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-09-09 19:44:07	ID requested
1	2021-09-09 19:44:18	announced
⏵ 2	2022-10-19 20:38:35	announced	2022-10-20: Update publication information.

Jiang PP, Peng SS, Pankratova S, Luo P, Zhou P, Chen Y, Proteins Involved in Synaptic Plasticity Are Downregulated in the Cerebrospinal Fluid of Infants With Clinical Sepsis Complicated by Neuroinflammation. Front Cell Neurosci, 16():887212(2022) [pubmed]

submitter keyword: neonatal sepsis, cerebrospinal fluid, proteomics, meningitis

Pingping Jiang
contact affiliation	Sun Yat-sen Univeristy
contact email	jiangpp3@mail.sysu.edu.cn
lab head
Shanshan Peng
contact affiliation	Sun Yat-sen University
contact email	pengshsh6@mail2.sysu.edu.cn
dataset submitter

iProX dataset URI