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PXD028364

PXD028364 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLung Adenocarcinoma (A549) Immunopeptidomics
DescriptionAlterations in cellular antigen processing and presenting machinery has gained increased interest as a hallmark of cancer-related inflammation. Growing evidence suggest that proteasome composition and immunoproteasome expression can influence antigen processing. By performing immunopeptidomics on A549 lung adenocarcinoma cell line following depletion of proteasome regulator PSME4 we identified alterations in the antigenic landscape resulting from changes in proteasome processing.
HostingRepositoryPRIDE
AnnounceDate2024-10-07
AnnouncementXMLSubmission_2024-10-07_10:56:07.689.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAaron Javitt
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; mono N-acetylated residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-09-09 08:29:27ID requested
12024-10-07 10:56:08announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: A549, NSCLC, Immunopeptidome,HLA
Contact List
Yifat Merbl
contact affiliationWeizmann Institute of Science
contact emailyifat.merbl@weizmann.ac.il
lab head
Aaron Javitt
contact affiliationWeizmann Institute of Science
contact emailaaron.javitt@weizmann.ac.il
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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