PXD028246

PXD028246 is an original dataset announced via ProteomeXchange.

Title	Human HEK293T cells LC-MS/MS (Gel-based proteomics)
Description	Fanconi Anemia (FA) pathway is essential for the repair of inter-strand crosslink (ICLs). ICL induces stalled replication forks and triggers activation of FA pathway for efficient ICL repair. Given that stalled replication fork is proximal to ICLs sites, fork-associated proteins may likely coordinate with FA factors to rapidly sense ICLs for activation of FA signaling. We will use LC-MS/MS to identify such proteins that participated in the ICL repairs.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:45:52.782.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	YI ZHANG
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ

Revision	Datetime	Status	ChangeLog Entry
0	2021-09-09 07:57:13	ID requested
1	2023-05-10 09:02:59	announced
⏵ 2	2023-11-14 08:46:01	announced	2023-11-14: Updated project metadata.

Zhang Y, Li J, Zhou Y, Li Z, Peng C, Pei H, Zhu W, And-1 Coordinates with the FANCM Complex to Regulate Fanconi Anemia Signaling and Cisplatin Resistance. Cancer Res, 82(18):3249-3262(2022) [pubmed]

submitter keyword: Fanconi Anemia Pathway,Human cells, WDHD1

Wenge Zhu
contact affiliation	The George Washington University, Department of Biochemisty and Molecular Medicine, Cacncer Center, D.C., 20037
contact email	wz6812@gwu.edu
lab head
YI ZHANG
contact affiliation	The George Washington University
contact email	scholarzy@gwu.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD028246

PRIDE project URI

• PRIDE
  1. PXD028246
     1. Label: PRIDE project
     2. Name: Human HEK293T cells LC-MS/MS (Gel-based proteomics)